-Nervousness including agitation, anxiety and irritability
-Trouble sleeping (insomnia)
-Decreased appetite
-Headache
-Stomach ache
-Nausea
-Dizziness
-Heart palpitations
Overdose Side EffectsMethylphenidate drugs have been extensively abused. Extreme psychological dependence and severe social disability have resulted. Abuse of methylphenidate drugs may cause a sudden heart attack even in those with no signs of heart disease. Symptoms of overdose that require immediate medical assistance include:
-Restlessness
-Aggression
-Hallucinations
-Panic states
-Hyperreflexia (overactive reflexes, which can include twitching or spasms)
-Personality changes
-Symptoms of depression
-Seizures or abnormal EEGs
-High blood pressure
-Rapid heart beat
-Swelling of hands/feet/ankles (for example, numbing of the fingertips)
-Delusions
-Sweating
-Vomiting
-Dehydration
-Unexplained muscle pain
-Lower abdominal pain
Other Serious Side Effects Include
-Slowing of growth (height and weight) in children
-Seizures, mainly in patients with a history of seizures
-Eyesight changes or blurred vision
-Less Common Side Effects
-High blood pressure
-Rapid pulse rate (and other heart problems)
-Tolerance (constant need to raise the dose)
-Feelings of suspicion and paranoia
-Visual hallucinations (seeing things that are not there)